Fig. 1. Testing of challenge virus stocks.

Groups of goats (3 animals per group) were infected with PPRV/Cote d’Ivoire/1989 (CdI), PPRV/Georgia/2016 (Georgia), PPRV/Ghana/Accra/1978 (Ghana) or PPRV/Iraq/2011 (Iraq) and monitored for 8-9 days post challenge to establish the pattern of clinical disease elicited by the challenge. a The rectal temperatures of the infected animals (recorded daily); (b) the clinical score based on the scoring table as described in “Methods”; (c) viral RNA as quantitated using RT-qPCR on blood samples or swabs taken approximately every two days. The position of the median of all the samples at a particular time is indicated by a horizontal bar, and the data points are coloured according to the PPRV strain used to infect the animal.