Table 1.
Characteristics of the 13 studies.
| Study | County | Study design | Age (year) | Male/female | Total patients | Cases number | Controls number | SAE incidence (%) | Sepsis diagnostic criteria | SAE assessment tools/diagnostic criteria |
|---|---|---|---|---|---|---|---|---|---|---|
| Li et al. (2011) | China | Case-control | 51.1 ± 27.1 | 164/120 | 284 | 107 | 177 | 37.68% | Sepsis2.0 | Data recorded by medical staff |
| Zhang et al. (2012) | China | Case-control | 51.5 ± 14.8 | 157/75 | 232 | 41 | 191 | 17.67% | Sepsis2.0 | Data recorded by medical staff |
| Zhao et al. (2019) | China | Cohort | 61.7 ± 13.0 | 64/45 | 109 | 27 | 82 | 24.77% | Sepsis1.0 | Data recorded by medical staff |
| Chen et al. (2023) | China | Cohort | 64.3 ± 15.5 | 61/29 | 90 | 57 | 33 | 63.33% | Sepsis3.0 | GCS <15 |
| Lu et al. (2016) | China | Cohort | 58.7 ± 8.4 | 57/29 | 86 | 34 | 52 | 39.53% | Sepsis2.0 | Data recorded by medical staff |
| Kristo et al. (2018) | Finland | Case-control | 64.2 ± 16.9 | 14/8 | 22 | 10 | 12 | 45.45% | Sepsis1.0 | CAM-ICU |
| Chen et al. (2020) | China | Case-control | 58.6 ± 20.1 | 213/78 | 291 | 127 | 164 | 43.64% | Sepsis3.0 | GCS <15 OR CAM-ICU |
| Jin et al. (2022) | China | Cohort | 75.3 ± 10.4 | 155/67 | 222 | 132 | 90 | 59.46% | Sepsis3.0 | GCS <15 OR CAM-ICU |
| Yeunwoo et al. (2020) | Korea | Case-control | 67.3 ± 15.0 | 95/80 | 175 | 107 | 68 | 61.14% | Sepsis1.0 | CAM-ICU |
| Feng et al. (2021) | China | Cohort | 53.0 ± 11.0 | 20/31 | 51 | 20 | 31 | 39.22% | Sepsis3.0 | CAM-ICU |
| Duc et al. (2014) | Belgium | Case-control | 65.0 ± 14.0 | 83/45 | 128 | 107 | 21 | 83.59% | Sepsis2.0 | GCS <15 OR CAM-ICU |
| Feng et al. (2017) | China | Cohort | 56.7 ± 15.0 | 107/68 | 175 | 74 | 101 | 42.29% | Sepsis1.0 | CAM-ICU |
| Li et al.(2022) | China | Case-control | 37.5 ± 4.5 | 18/23 | 41 | 21 | 20 | 51.22% | Diagnostic criteria for burn infection | Data recorded by medical staff |