Table 4.

Comparison of antimicrobial resistance genes and plasmid replicon types from K. pneumoniae of human and dog origin.

	Human isolates and their plasmids							Dog isolates and their plasmids
	KPH1		KPH3		KPH4			KPA1			KPA2				KPA3
	pKPH1_1 (132,031 bp)	pKPH1_2 (125,297 bp)	pKPH3_1 (108,736 bp)	pKPH3_2 (41,190 bp)	pKPH4_1 (77,911 bp)	pKPH4_2 (42,965 bp)	pKPH4_3 (6,141 bp)	pKPA1_1 (111,444 bp)	pKPA1_2 (68,908 bp)	pKPA1_3 (6,141 bp)	pKPA2_1 (188,688 bp)	pKPA2_2 (160,519 bp)	pKPA2_3 (82,102 bp)	pKPA2_4 (6,141 bp)	pKPA3_1 (175,819 bp)	pKPA3_2 (121,101 bp)
Accession No. (*NCBI)	CP102547	CP102548	CP102553	CP102555	JAOAOE010000005	JAOAOE010000006	JAOAOE010000009	CP101878	CP101880	CP101881	CP102988	CP102989	CP102990	CP102991	CP102994	CP102995
Plasmid replicon types	IncFIB(pQil) IncFII(K)	IncFIA IncFIB IncFII	IncFIA(HI1) IncR	IncN2	IncFII	IncN	ColKP3	IncFIA IncFIB IncFII	IncFII	ColKP3	IncFIB(K)	IncC	Unknown	ColKP3	IncFIB(pQil) IncFII(K)	IncFIB(K) IncHI1B
Resistance genes
β-lactam	bla CTX-M-15 bla TEM-1A bla OXA-9	bla NDM-1	bla CTX-M-15 bla TEM-1B bla OXA-1 bla SHV-12	bla NDM-1		bla TEM-1B	bla OXA-232		bla OXA-48	bla OXA-232	bla DHA-1	bla CMY-2	bla TEM-1B bla CTX-M-3	bla OXA-232	bla NDM-1
Aminoglycoside	aadA1 aac(6′)-Ib	aadA2	aph(3″)-Ib aac(3)-IIa aph(6)-Id		aac(3)-VIa aadA1			aadA2			aph(3′)-Ia	aac(6′)-Ib3 aph(6)-Id aph(3″)-Ib ant(2″)-Ia aac(6′)-Ip	aadA16 rmtB		rmtF
Quinolones	qnrB1 aac(6′)-Ib-cr		aac(6′)-Ib-cr		qnrS1	qepA1 qepA2 qepA4					qnrB4	qnrVC4 aac(6′)-Ib-cr	qnrS1		qnrB1 aac(6′)-Ib-cr
Trimethoprim		dfrA12	dfrA14					dfrA12					dfrA27
Sulphonamide		sul1	sul2					sul1				sul2	sul1
Tetracycline		tet(B)	tet(A) tet(D)					tet(B)				tet(A) tet(M)				tet(D)
Phenicol			catB3 catA2									floR cmlA1				catA1
Colistin					mcr-3.5
Macrolide											mph(A)
Rifampicin													ARR-3		ARR-2
Biocide		qacE						qacE			qacE	qacL	qacE

^*National Center for Biotechnology Information database.