FIG. 7.

Determination of the AI and expression of PCNA in transiently and chronically infected woodchucks. (A) The results of determinations of apoptotic cells counts from slides of tissue from woodchucks 22 and 36 at the indicated time points. (B) The results of determinations of apoptotic cell counts of cohort II animals prior to infection (P) and 4 weeks p.i. (4). Panel B also shows the results obtained with two uninfected control animals, 2598 and 2732, and four chronically infected woodchucks, 4705, 4707, 4714, and 4723. The AI is the fraction (percentage) of apoptotic hepatocytes per normal hepatocyte. (C) The results of the analysis of PCNA-positive hepatocytes of sections from cohort II animals and the four chronically infected woodchucks.