Figure 3.

Top-ranked genes selected from the machine learning model and pathway enrichment analysis

(A) GO cluster analysis showing pathways based on genes obtained from T1D vs. CTL comparison across unannotated all cells.

(B) Top 20 KEGG pathways based on ranked genes obtained from T1D vs. CTL comparison across all cells (unannotated) and different cell types (annotated) (Table S3).

(C) UpSetR chart showing the common and unique count of genes across annotated cells in T1D vs. CTL comparison.

(D) Pathways based on shared RRA_combined gene list in T1D vs. CTL annotated cells.

(E) UpSetR chart showing the common and unique count of genes across annotated cells in T1D vs. AAb+ comparison.

(F) UpSetR chart showing the common and unique count of genes across annotated cells in AAb+ vs. CTL comparison.