REAGENT or RESOURCE	SOURCE	IDENTIFIER
Biological samples
SLE and control plasma or serum samples	Patients and healthy control subjects	N/A
Critica commercia assays
HEK-BlueTM IFN-α/β cells	InvivoGen	Cat# hkb-ifnab; RRID: CVCL_KT26
HEK-Blue™ IFN-γ cells	InvivoGen	Cat# hkb-ifng; RRID: CVCL_UF30
HEK-Blue™ IFN-λ cells	InvivoGen	Cat# hkb-ifnl
QUANTI-Blue™	InvivoGen	Cat# rep-qb1
IFN-α6	PBL	Cat# 11165
IFN-γ	PeproTech	Cat# 300-02
IFN-λ3 (IL-28B)	Gibco	Cat# PHC0894
Deposited data
Whole blood gene expression data by microarray	Gene expression Omnibus	GSE45291; GSE121239
Softwareand algorithms
Oligo	https://bioconductor.org/packages/release/bioc/html/oligo.html	Ver. 1.6.6
Genefilter	https://bioconductor.org/packages/release/bioc/html/genefilter.html	Ver. 1.84
Limma	https://bioconductor.org/packages/release/bioc/html/limma.html	Ver. 3.58.1
Metascape.org	https://metascape.org/	v3.5.20240101
Complexheatmap	https://bioconductor.org/packages/devel/bioc/html/ComplexHeatmap.html	Ver. 2.19.0
WGCNA	https://cran.r-project.org/web/packages/WGCNA/index.html	Ver. 1.72–5
Cytoscape	https://cytoscape.org/	Ver. 3.10.2
STRING	https://apps.cytoscape.org/apps/stringapp	Ver. 2.0.3
rptR	https://github.com/mastoffel/rptR	Ver.0.9.1
Brms	https://github.com/paul-buerkner/brms/	Ver.2.21.0
Lme4	https://github.com/lme4/lme4	Ver. 1.1–14
nnet	https://cran.r-project.org/web/packages/nnet/index.html	Ver. 7.3–19