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. 2024 May 20;7:19. doi: 10.20517/cdr.2024.04

Figure 6.

Figure 6

Effect of (A) 1-h and (B) 48-h treatments with different concentrations of pentoxifylline on P-gp activity of the NCI-H460/R cells, determined by the Rhodamine-123 accumulation assay. NCI-H460 cells were used as a negative control. The positive control consisted of NCI-H460/R cells treated with 20 μM verapamil. **P < 0.01; ***P < 0.001; ****P < 0.0001. P-gp: P-glycoprotein.