TABLE 2.
Univariable and Multivariable Linear Regression Assessing Association of Hemoglobin With Viscoelastic Hemostatic Assay Results in Intracerebral Hemorrhage Patients
| Rotational Thromboelastometry Outcome | Unadjusted Beta Coefficient (95% CI) p |
Adjusted Beta Coefficient (95% CI) pa |
Thromboelastography Outcome | Unadjusted Beta Coefficient (95% CI) p |
Adjusted Beta Coefficient (95% CI) pa |
|---|---|---|---|---|---|
| EXTEM CT (s) | 0.26 (−0.71 to 4.79) p = 0.14 |
0.17 (−1.95 to 4.28) p = 0.45 |
Reaction time (min) | 0.06 (−0.05 to 0.15) p = 0.34 |
0.03 (−0.08 to 0.12) p = 0.67 |
| EXTEM CFT (s) | 0.40 (0.61–6.85) p = 0.02 |
0.49 (1.03–7.71) p = 0.01 |
Kinetics time (min) | 0.31 (0.09–0.21) p < 0.0001 |
0.30 (0.09–0.21) p < 0.0001 |
| EXTEM alpha (degrees) | −0.56 (−1.69 to −0.49) p = 0.001 |
−0.59 (−1.79 to −0.49) p = 0.001 |
Alpha (degrees) | −0.45 (−2.04 to −1.21) p < 0.0001 |
−0.44 (−2.06 to −1.17) p < 0.0001 |
| EXTEM MCF (millimeters) | −0.29 (−2.09 to 0.21) p = 0.11 |
−0.42 (−2.62 to −0.07) p = 0.04 |
Maximum amplitude (millimeters) | −0.39 (−1.97 to −1.05) p < 0.0001 |
−0.39 (−2.01 to −1.05) p < 0.0001 |
| EXTEM ML (%) | NA | NA | Lysis index (%) | −0.13 (−0.17 to 0.001) p = 0.05 |
−0.10 (−0.16 to 0.02) p = 0.14 |
| INTEM CT (s) | 0.03 (−10.78 to 12.99) p = 0.85 |
−0.02 (−14.95 to 13.90) p = 0.94 |
|||
| INTEM CFT (s) | −0.13 (−9.34 to 4.48) p = 0.48 |
−0.12 (−10.85 to 6.23) p = 0.58 |
|||
| INTEM alpha (degrees) | 0.07 (−0.84 to 1.27) p = 0.68 |
0.07 (−1.11 to 1.52) p = 0.75 |
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| INTEM MCF (millimeters) | −0.09 (−1.47 to 0.85) p = 0.59 |
−0.05 (−1.59 to 1.29) p = 0.83 |
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| INTEM ML (%) | NA | NA | |||
| Fibrinogen assay MCF (millimeters) | −0.06 (−2.08 to 1.51) p = 0.75 |
0.02 (−2.09 to 2.27) p = 0.94 |
CFT = clot formation time, CT = coagulation time, EXTEM = extrinsic pathway assay, INTEM = intrinsic pathway assay, MCF = maximal clot firmness, ML = maximum lysis, NA = not available.
a
Adjusted for age, sex, baseline hematoma size, and antiplatelet medication use.