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. 2024 Jun;65(6):971–979. doi: 10.2967/jnumed.123.266686

TABLE 3.

Comparison with Literature Values for 18F-FDG MR, Vd, and Vb in Different Tissues from Equation 4

Parameter Method GM WM Lung Liver Spleen Kidney Bones
18F-FDG MR (μmol/100 g/min) Voxel-NP 18.54 ± 6.81 6.66 ± 2.44 0.42 ± 0.31 1.40 ± 0.53 1.40 ± 0.94 2.52 ± 1.51 1.63 ± 0.63
VOI-2C* 18.98 ± 7.18 6.83 ± 2.26 0.43 ± 0.32 1.38 ± 0.47 1.08 ± 1.24 1.19 ± 1.43 1.58 ± 0.55
20.26 ± 6.14 7.17 ± 2.09 0.47 ± 0.35 1.39 ± 0.89 1.39 ± 0.83 1.98 ± 2.20 1.72 ± 0.63
22.22 ± 2.71 7.60 ± 1.58 0.60 ± 0.42 5.22 ± 2.67 9.40 ± 4.57 9.15 ± 6.44 1.34 ± 0.46
17.46 [11.68–27.61] 6.03 [4.02–9.53] 0.35 [0.03–1.74] 2.02 [0.74–4.35] 2.45 [1.18–15.30] 3.81 [0.08–7.95] 3.69 [1.08–9.09]
Vd (mL/g) Voxel-NP 0.88 ± 0.26 0.64 ± 0.27 0.09 ± 0.03 0.86 ± 0.08 0.42 ± 0.09 1.20 ± 0.34 0.22 ± 0.07
VOI-2C 0.56 ± 0.23 0.55 ± 0.16 0.09 ± 0.03 0.88 ± 0.09 0.49 ± 0.12 1.25 ± 0.36 0.20 ± 0.06
0.62 ± 0.56 0.67 ± 0.22 0.26 ± 0.06 0.98 ± 0.15 0.63 ± 0.14 1.44 ± 0.55 0.23 ± 0.10
0.81 [0.14–1.41] 0.46 [0.15–0.87] 0.15 [0.02–0.28] 0.84 [0.44–1.26] 0.58 [0.10–1.12] 0.96 [0.33–1.41] 0.31 [0.04–0.51]
Vb (mL/min/g) Voxel-NP 0.43 ± 0.11 0.24 ± 0.08 1.41 ± 0.32 0.73 ± 0.34 1.70 ± 0.74 1.99 ± 0.58 0.22 ± 0.12
VOI-2C 0.26 ± 0.04 0.13 ± 0.04 1.16 ± 0.34 0.14 ± 0.07 0.85 ± 0.42 1.22 ± 0.38 0.03 ± 0.02
0.59 ± 0.11 (32) 0.20 ± 0.04 (32) 1.40 ± 0.30 (33) 1.11 ± 0.34 (34) 1.92 ± 0.76 (35) 1.74 ± 0.44 (35) 0.18 ± 0.03 (36)
0.41 ± 0.11 (37) 0.22 ± 0.04 (37) 1.21 ± 0.32 (38) 1.78 ± 0.56 (39) 1.68 ± 0.12 (40) 1.57 ± 0.60 (41) 0.18 ± 0.05 (42)
*

References 2,4,27,30,31.

References 2,27.

GM = gray matter; WM = white matter; Voxel-NP = VOI-averaged voxel kinetics; VOI-2C = VOI time course kinetics obtained by 2C analysis.

Data are mean ± SD, or median followed by range in brackets.