Table 2.
BSI Outcomes
BSI Information | Value |
---|---|
Hurler patients with a BSI, n/N (%) | 12/25 (48) |
Total BSIs | 16 |
BSIs by stem cell source, n/N (%) | |
Cord blood | 10/16 (63) |
Bone marrow | 6/16 (37) |
BSIs by conditioning regimen, n/N (%) | |
MAC | 11/16 (69) |
RIC | 5/16 (31) |
BSIs by HLA matching, n/N (%) | |
Matched related | 1/16 (6) |
Matched unrelated | 11/16 (69) |
Mismatched unrelated | 4/16 (25) |
Infection type, n/N (%) | |
Monomicrobial infections | 3/16 (81) |
Polymicrobial infections | 3/16 (19) |
Organisms identified, n (%) | 20 |
Staphylococcus aureus | 4 (20) |
Klebsiella pneumoniae | 3 (15) |
Escherichia coli | 2 (10) |
Staphylococcus epidermidis | 2 (10) |
Actinomyces odontolyticus | 1 (5) |
Enterococcus faecalis | 1 (5) |
Moraxella osloensis | 1 (5) |
Pseudomonas aeruginosa | 1 (5) |
Coagulase-negative Staphylococcus | 1 (5) |
Staphylococcus haemolyticus | 1 (5) |
Streptococcus agalactiae | 1 (5) |
Streptococcus mitis/oralis | 1 (5) |
Streptococcus viridans | 1 (5) |
Time to infection, d, median (IQR) | 33 (6.5–128.5) |
MAC indicates myeloablative conditioning; RIC, reduced-intensity conditioning.