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. Author manuscript; available in PMC: 2024 Jun 4.
Published in final edited form as: Nat Genet. 2024 Mar 20;56(4):697–709. doi: 10.1038/s41588-024-01692-z

Extended Data Figure 2: DUXBL does not function as a transcriptional activator.

Extended Data Figure 2:

a) Volcano plots showing differentially expressed genes between DUX- (left panel) or DUXBL-expressing ESC (right panel) compared to control ESC. b) Heatmap showing the top 50 differentially expressed genes between DUX- and DUXBL-expressing ESC. c) Western blot analysis of the indicated proteins performed with V5 immunoprecipitates obtained from 293T cells transfected with the corresponding expression vectors. This experiment was repeated multiple times, but one is shown. Data in (a, b) was generated using three replicates per condition.