Figure 1.

Flowchart of recruitment, enrollment, and study completion. Eligible patients were identified based on chart review in the Marshfield Clinic Health System, in addition to setting up a phone hotline for interested participants from other health systems. After exclusions and searching specifically for patients with clinical isolates available, 284 patients were contacted for enrollment. Of those contacted, 83% enrolled in our cohort. Within the cohort, 85% consented to SNP genotyping, and 51% had genotyped clinical isolates of Blastomyces.