Table 1.
Differences in patient demographics, underlying medical conditions, and clinical presentation associated with Blastomyces species. we identified the species of Blastomyces as a significant variable explaining differences in clinical progression between patients diagnosed with blastomycosis. Demographic variables and co-morbidities were not associated with Blastomyces species, but several symptoms were significantly associated with species.
| Variable category | Variable tested | B. gilchristii (80 patients) | B. dermatitidis (40 patients) | P value | 95% Confidence Interval |
|---|---|---|---|---|---|
| Demographics | |||||
| Gender | 59% male | 63% male | 0.84 | −24 – 17% | |
| Smoking (past or current) | 38% | 58% | 0.35 | −11 – 34% | |
| Underlying Conditions | |||||
| Cardiac | 29% | 45% | 0.12 | −36 – 4% | |
| Pulmonary | 9% | 18% | 0.27 | −24 – 6% | |
| Neurological | 4% | 10% | 0.34 | 4 – 10% | |
| Diabetes | 11% | 13% | 1.00 | −15 – 12% | |
| Immunocompromised | 14% | 18% | 0.79 | −20 – 12% | |
| Obesity | 51% | 38% | 0.36 | −7 – 35% | |
| Symptoms | |||||
| Fever | 79% | 35% | < 0.01 | −63 – −25% | |
| Fatigue | 60% | 33% | 0.01 | −47 – −8% | |
| Cough | 94% | 78% | 0.02 | −32 – −0.4% | |
| Chest pain | 54% | 33% | 0.05 | −41 – −1% | |
| Shortness of breath | 65% | 21% | 0.03 | −43 – −2% | |
| Skin lesion | 6% | 35% | < 0.01 | 12 – 46% | |