Fig. 2.

Multi-omics analysis of zinc homeostasis regulators at the pan-cancer level. A Identification of DFS-related ZHRGs in TCGA-PRAD. B Cox regression analysis and log-rank test on DFS in different cancers. C Genomic positions of ZHRGs. D Association network based on the expression of ZHRGs. E Oncoplot displaying the SNV profiles of ZHRGs. F Mutational frequencies of ZHRGs in 20 tumors. G CNV alterations of each ZHRG. H Associations between the expression of ZHRGs and CNV alterations. I Differences in promoter methylation levels between tumor and normal samples. J Correlations between the expression of ZHRGs and promoter methylation levels