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. 2024 Jun 4;15:207. doi: 10.1007/s12672-024-01006-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Biological peculiarities of the two subtypes. A Differential expression analysis for transcriptomes between the two subtypes. B-C Proteomaps demonstrating functional analysis in B ZHPS1 and C ZHPS2 based on the KEGG database. D-F GO enrichment analysis for D biological process, E cellular component and F molecular function. G Differences in Hallmark pathways through GSVA between ZHPS2 and ZHPS1. H GSEA of the Reactome pathways (ZHPS2 versus ZHPS1). I-K Estimated IC50 values of I abiraterone, J docetaxel and K olaparib

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