Table 2.
Variables associated with developmental disorders
| Variables | No developmental disorders (n. 46) |
developmental disorders (n. 7) |
P |
|---|---|---|---|
| Age at diagnosis | 26.6 ± 6.0 | 29.0 ± 7.1 | 0.351 |
| Age at pregnancy | 32.1 ± 5.3 | 34.1 ± 7.1 | 0.379 |
| Microadenoma; n (%) | 36 (78%) | 6 (86%) | 0.962 |
| Adenoma maximum diameter at diagnosis (mm); median [IQR] | 7 [5;9] | 6 [6;6] | 0.731 |
| Prolactin levels at diagnosis (ng/ml); median [IQR] | 121 [53–221] | 65 [48.5–87.7] | 0.097 |
| Adenoma diameter nadir before pregnancy (mm); median [IQR] | 5.8 [4.5–8.0] | 4.0 [0.0–6.0] | 0.096 |
| Prolactin levels nadir before pregnancy (ng/ml); median [IQR] | 10.2 [4.7;21.2] | 4.5 [0.9;19.4] | 0.265 |
| Breastfeeding (yes); n (%) | 29 (63%) | 5 (71%) | 0.994 |
| Breastfeeding duration (weeks); median [IQR] | 4 [0–24] | 2 [0–39] | 0.669 |
| Foetal Exposure to DA (days); median [IQR] | 28 [28–35] | 28 [28–35] | 0.770 |
|
CAB; n (%) BRM; n (%) |
31 (67.4%) 15 (32.6%) |
7 (100%) 0 (0%) |
0.171 |
| Child weight at birth (gr); median [IQR] | 3350 [3062–3692] | 3530 [3295- 3652] | 0.874 |
| Delivery/pregnancy complications (yes); n (%) | 11 (24%) | 2 (29%) | 0.937 |
| APGAR SCORE; median [IQR] | 9 [9–9] | 9 [9–9] | 0.205 |
| APGAR SCORE | 0.386 | ||
| ≤ 6 | 0 | 0 | |
| 7 | 1 | 0 | |
| 8 | 1 | 1 | |
| 9 | 26 | 6 | |
| 10 | 6 | 0 |
IQR interquartile range; SD standard deviation, DA dopamine agonist