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. 2024 Jun 4;15(6):392. doi: 10.1038/s41419-024-06706-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Relative mRNA levels of CYP24A1, FBP1, HRNR, GAST and TNFRSF10C in control (0 mJ/cm²) and UVB-irradiated (500 mJ/cm²) human epidermal equivalents collected 72 h after irradiation, n = 3 or 4 independent experiments. b Representative H&E staining or immunohistochemical staining (FBP1, K10) of control (0 mJ/cm²) or UVB (500 mJ/cm²) irradiated human epidermal equivalents collected 72 h after irradiation. Scale bars: 50 μm. c Representative immunohistochemical staining for FBP1 of control (0 mJ/cm²) or UVB (500 mJ/cm²) irradiated mice skin collected 72 h after irradiation. Scale bars: 50 μm. Arrows indicated deep-stained upper epidermis. d Representative H&E staining or immunohistochemical staining of mice skin collected at indicated days after irradiation. Scale bars: 50 μm. Data are shown as mean ± s.d. Statistical analyses in (a) were performed with Student’s t-tests. *p < 0.05, **p < 0.01.