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. 2024 May 22;14:1375882. doi: 10.3389/fonc.2024.1375882

Table 3.

Evaluation of lymph node involvement stage [as stated in the AJCC Cancer Staging Manual, 7th ed (46), NCCN 1.2024 (44) and Sanchez et al., 2022 (45)].

Regional Lymph Node (N) involvement
Pathological Clinical
pNX Regional lymph nodes cannot be assessed cNX Regional lymph nodes cannot be assessed
pN0 No regional lymph node metastasis cN0 No palpable or visibly large inguinal lymph nodes
pN1 Metastasis in a single superficial inguinal lymph node cN1 Unilateral mobile palpable inguinal lymph nodes
pN2 Metastasis in multiple or bilateral superficial inguinal lymph nodes cN2 ≥ 2 unilateral mobile palpable or bilateral palpable inguinal lymph nodes
pN3 Metastasis in unilateral or bilateral deep inguinal lymph nodes cN3 Uni- or bilateral palpable fixed inguinal mass or pelvic lymphadenopathy