Figure 8.
Effect of the classical ketogenic diet on epilepsy onset in patients with epilepsy. CAU, conventional epilepsy diet group; KD, classical ketogenic diet group. (A) EEG of patients with epilepsy, n = 30, and the vertical arrow indicates the beginning and end of epileptic seizures in mice. (B) Frequency of epilepsy in patients with epilepsy, n = 30, * indicates the comparison between the two groups, p < 0.05. (C) Duration of epilepsy in patients with epilepsy, n = 50, * indicates the comparison between the two groups, p < 0.05. (D) Glucose concentration levels, n = 50, * indicates the comparison between the two groups, p < 0.05. (E) β-hydroxybutyrate levels, n = 50, * indicates the comparison between the two groups, p < 0.05. (F) Influence of KD on blood lipid levels in patients with epilepsy, n = 30, TG (triglycerides), HyperChol (cholesterol), HDL (high-density lipoprotein), LDL (low-density lipoprotein), ns indicates the comparison between the two groups, p > 0.05. (G) Expression of ADCY3, cAMP, and PKA in the blood of patients with epilepsy detected by ELISA, n = 30, * indicates the comparison between the two groups, p < 0.05.
