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. 2023 Dec 5;6(5):677–688. doi: 10.1016/j.cjco.2023.11.024

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© 2023 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Forest plot of (A) major adverse cardiovascular events, (B) all-cause death, (C) stent thrombosis, and (D) major bleeding with ticagrelor-, compared with prasugrel-based, dual antiplatelet therapy in patients with acute coronary syndrome treated with percutaneous coronary intervention (PCI). CI, confidence interval; df, degrees of freedom; DUBIUS, Downstream vs Upstream Strategy for the Administration of P2Y₁₂ Receptor Blockers In Non-ST Elevated Acute Coronary Syndromes With Initial Invasive Indication; ISAR-REACT 5, Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment 5; M-H, Mantel–Haenszel; PRAGUE-18, Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial Infarction; RAPID, Rapid Activity of Platelet Inhibitor Drugs; REDUCE-MVI, Reducing Microvascular Dysfunction in Revascularized STEMI Patients by Off-Target properties of Ticagrelor.

Forest plot of (A) major adverse cardiovascular events, (B) all-cause death, (C) stent thrombosis, and (D) major bleeding with ticagrelor-, compared with prasugrel-based, dual antiplatelet therapy in patients with acute coronary syndrome treated with percutaneous coronary intervention (PCI). CI, confidence interval; df, degrees of freedom; DUBIUS, Downstream vs Upstream Strategy for the Administration of P2Y₁₂ Receptor Blockers In Non-ST Elevated Acute Coronary Syndromes With Initial Invasive Indication; ISAR-REACT 5, Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment 5; M-H, Mantel–Haenszel; PRAGUE-18, Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial Infarction; RAPID, Rapid Activity of Platelet Inhibitor Drugs; REDUCE-MVI, Reducing Microvascular Dysfunction in Revascularized STEMI Patients by Off-Target properties of Ticagrelor.