Table 11. Statins and Cardiovascular and Metabolic Drugs Metabolized by CYPs.

CYP	Statins Metabolized by CYPs	Cardiovascular and Metabolic Drugs Metabolized by CYPs
CYP3A4	Atorvastatin	Calcium channel blockers (diltiazem, verapamil, nifedipine, amlodipine, cilnidipine, azelnidipine, benidipine), warfarin, repaglinide＊
	Simvastatin
CYP2C9	Fluvastatin	ARBs (losartan, valsartan, candesartan, irbesartan, azilsartan), warfarin, glinides (nateglinide, mitiglinide), glimepiride

^＊Repaglinide is mainly metabolized by CYP2C8, but CYP3A4 is also involved in some cases.