Figure 1. Network Plot Comparing Each Treatment With the Common Comparator Long-Course Chemoradiotherapy With Single-Agent Fluoropyrimidine (L-CRT1) for Primary Outcome Pathological Complete Response.

The thickness of lines is proportional to the number of studies comparing the 2 treatments, and the size of circles is proportional to the number of individuals for each treatment. CHT indicates chemotherapy; induction + L-CRT, induction CHT plus consolidation L-CRT; L-CRT + consolidation, L-CRT plus consolidation CHT; L-CRT2, L-CRT with duplex CHT drug (fluoropyrimidine plus oxaliplatin); L-RT, long-course radiotherapy; S-RT + consolidation, short-course RT plus consolidation CHT; S-RTdelayed, S-RT plus delayed rectal resection; S-RTearly, S-RT plus early rectal resection.