Table 1. Inclusion and exclusion criteria for the screening of studies based on the PICO model .

PICO: population, intervention, comparison, and outcomes

Study characteristics	Inclusion criteria	Exclusion criteria
Population	Adult population diagnosed with onychomycosis disease	Adult population with other nail infections or participants with non-onychomycosis disease
Intervention	Laser treatment against onychomycosis	Other treatment strategies such as topical agents against onychomycosis
Comparison	Laser treatment versus terbinafine treatment against onychomycosis	Laser treatment versus placebo or other treatment against onychomycosis
Outcomes	Mycological cure rates, clinical improvement, and adverse effects	No primary or secondary outcomes of interest