TABLE 3.
Relative susceptibility of nonhuman cell lines to infection by PERV-NIH-2°-derived PERV pseudotypes
| Species of origin | Cell line | % Controla |
|---|---|---|
| Mus musculus molossinus | MMK | 0 |
| M. musculus | SC-1 | 0 |
| M. dunni | MDTF | 0 |
| Rat | NRK | 0 |
| Rat | Rat-2 | 0.1 |
| Rabbit | SIRC | 0 |
| Dog | D17 | 0 |
| Cow | MDBK | 0 |
| Rhesus monkey | FRhK4 | 0 |
| Mink | Mv1Lu | 18, 53 |
| MiCL.1 | 5 | |
| Cat | PG-4 | 81, 90 |
| Fc3TG | 3, 6 | |
| AK-D | 1.3, 1.6 | |
| CRFK | 7, 6.1 |
a
Results were normalized to the infectivity titer observed on 293 cells exposed to the same PERV-NIH-2°-containing supernatant (see Materials and Methods). Titers on 293 cells varied from 500 to 3,000 BFU/ml in different experiments. In those cases where 0 is reported, no β-galactosidase-positive cells were observed after exposure of 30,000 to 40,000 cells to 1.0 ml of virus-containing supernatant. In those where a second independent experiment was carried out to verify the result, the results from both experiments are shown.