Table 3. Sensitivity, specificity and likelihood ratios for predicting malignancy of CA 125 serum levels, ultrasound score, menopausal status and the risk-of-malignancy index.
Variables | Sensitivity (%) |
95% CI | Sensitivity (%) |
95% CI | Likelihood Ratio (+) |
Likelihood Ratio (-) |
---|---|---|---|---|---|---|
CA 125 (u/ml) * | ||||||
10 | 94 | (84 - 98) | 26 | (17 - 37) | 1.27 | 0.23 |
35 | 78 | (65 - 86) | 75 | (64 - 83) | 3.12 | 0.29 |
50 | 61 | (48 - 73) | 88 | (78 - 94) | 5.08 | 0.44 |
65 | 52 | (39 - 64) | 91 | (82 - 96) | 5.77 | 0.53 |
150 | 27 | (17 - 39) | 97 | (89 - 99) | 9.00 | 0.75 |
Ultrasound Score * | ||||||
1 | 98 | (90 - 99) | 24 | (16 - 35) | 1.29 | 0.08 |
2 | 82 | (70 - 90) | 67 | (56 - 76) | 2.48 | 0.27 |
3 | 75 | (62 - 84) | 71 | (60 - 80) | 2.59 | 0.35 |
4 | 75 | (62 - 84) | 73 | (62 - 81) | 2.78 | 0.34 |
8 | 43 | (31 - 56) | 89 | (80 - 94) | 3.91 | 0.64 |
Postmenopausal | ||||||
Status | 73 | (60-83) | 69 | (58-78) | 2.35 | 0.39 |
Risk of malignancy index * | ||||||
30 | 96 | 56 | 2.18 | 0.07 | ||
100 | 84 | 77 | 3.65 | 0.21 | ||
150 | 79 | 79 | 3.76 | 0.27 | ||
200 | 73 | 86 | 5.21 | 0.31 | ||
500 | 63 | 97 | 21.00 | 0.38 |
Cut-off point;
CI: Confidence Interval.