TABLE 1.
Demographics, Clinical Characteristics, and Outcomes of Infants With and Without EOS
| Overall (N = 84 333) | Infected (EOS) (n = 1139) | Not Infected (No EOS) (n = 83 191) | |
|---|---|---|---|
| Maternal characteristics | |||
| Race and/or ethnicity | |||
| Black, non-Hispanic | 26 109/83 539 (31.2) | 375/1124 (33.4) | 25 734/82 415 (31.2) |
| Hispanic | 16 320/83 539 (19.5) | 247/1124 (22.0) | 16 073/82 415 (19.5) |
| White, non-Hispanic | 34 293/83 539 (41.1) | 402/1124 (35.8) | 33 893/82 415 (41.2) |
| Asian American, non-Hispanic | 4332/83 539 (5.2) | 57/1124 (5.1) | 4275/82 415 (5.2) |
| American Indian, non-Hispanic | 690/83 539 (0.8) | 8/1124 (0.7) | 682/82 415 (0.8) |
| Other, non-Hispanic | 1793/83 539 (2.2) | 35/1124 (3.1) | 1758/82 415 (2.1) |
| Any prenatal care | 80 822/84 018 (96.2) | 1067/1133 (94.2) | 79 755/82 885 (96.2) |
| Hypertensive disorder | 31 830/83 887 (37.9) | 170/1126 (15.1) | 31 660/82 761 (38.3) |
| Chorioamnionitis | 10 849/83 600 (13.0) | 515/1121 (45.8) | 10 034/82 479 (12.5) |
| Diabetes | 9179/83 734 (11.0) | 103/1128 (9.2) | 9076/82 606 (11.0) |
| Antenatal steroids | 73 691/83 977 (87.8) | 977/1134 (86.3) | 72 714/82 843 (87.8) |
| Multiple gestation | 20 555/84 329 (24.4) | 177/1139 (15.6) | 20 378/83 190 (24.5) |
| Cesarean delivery | 62 594/84 322 (74.2) | 659/1139 (57.9) | 61 935/83 183 (74.5) |
| Infant characteristics | |||
| BW, n | 84 325 | 1139 | 83 186 |
| Median (Q1, Q3), g | 1100 (810, 1330) | 870 (650, 1170) | 1100 (819, 1334) |
| GA, n | 84 329 | 1139 | 83 190 |
| ≤23 wk | 4908/84 329 (5.8) | 223/1139 (19.6) | 4685/83 190 (5.6) |
| 24–25 wk | 12 482/84 329 (14.8) | 324/1139 (28.5) | 12 158/83 190 (14.6) |
| 26–27 wk | 16 574/84 329 (19.7) | 259/1139 (22.7) | 16 315/83 190 (19.6) |
| 28–29 wk | 22 762/84 329 (27.0) | 229/1139 (20.1) | 22 533/83 190 (27.1) |
| >29 wk | 27 603/84 329 (32.7) | 104/1139 (9.1) | 27 499/83 190 (33.1) |
| Median (Q1, Q3), wk | 28 (26, 30) | 26 (24, 28) | 28 (26, 30) |
| Apgar score at 1 min, n | 83 416 | 1113 | 82 303 |
| Median (Q1, Q3) | 5 (3, 7) | 3 (1, 5) | 5 (3, 7) |
| SGA | 16 048/84 009 (19.1) | 48/1123 (4.3) | 16 000/82 886 (19.3) |
| Female sex | 41 802/84 310 (49.6) | 528/1139 (46.3) | 41 275/83 171 (49.6) |
| Outborn | 11 396/84 333 (13.5) | 180/1139 (15.8) | 11 216/83 194 (13.5) |
| Congenital anomaly | 4953/84 311 (5.9) | 49/1139 (4.3) | 4904/83 172 (5.9) |
| Infant individual outcomes | |||
| NEC | 3967/84 307 (4.7) | 69/1139 (6.1) | 3898/83 168 (4.7) |
| CLD | 20 474/69 219 (29.6) | 315/746 (42.2) | 20 159/68 473 (29.4) |
| Late-onset sepsis | 7184/81 149 (8.9) | 156/946 (16.5) | 7028/80 203 (8.8) |
| Pneumothorax | 3895/84 290 (4.6) | 105/1138 (9.2) | 3790/83 152 (4.6) |
| Severe IVH | 6206/76 270 (8.1) | 342/990 (34.6) | 5864/75 280 (7.8) |
| Cystic PVL | 2039/76 288 (2.7) | 76/990 (7.7) | 1963/75 298 (2.6) |
| Total length of stay among survivors, n | 75 596 | 763 | 74 833 |
| Median (Q1, Q3), d | 66 (45, 96) | 92 (66, 123) | 66 (45, 95) |
| By GA | |||
| ≤23 wk, n | 2538 | 106 | 2422 |
| Median (Q1, Q3), d | 143 (122, 175) | 148 (124, 194) | 143 (122, 174) |
| 24–25 wk, n | 9539 | 191 | 9348 |
| Median (Q1, Q3), d | 115 (98, 142) | 115 (97, 146) | 115 (98, 141) |
| 26–27 wk, n | 14 941 | 191 | 14 750 |
| Median (Q1, Q3), d | 87 (73, 107) | 90 (75, 105) | 87 (73, 107) |
| 28–29 wk, n | 21 777 | 187 | 21 590 |
| Median (Q1, Q3), d | 63 (52, 78) | 64 (53, 81) | 63 (52, 78) |
| >29 wk, n | 26 807 | 88 | 26 719 |
| Median (Q1, Q3), d | 40 (31, 52) | 46 (37, 65) | 40 (31, 52) |
Data are presented as numerator/denominator (%) unless otherwise stated. Q1, quartile 1; Q3, quartile 3.