TABLE 1.
Demographics and Clinical Characteristics of Infants With and Without Late-Onset Sepsis (N = 118 650)
| Overall | Late-Onset Sepsis | No Late-Onset Sepsis | |||||||
|---|---|---|---|---|---|---|---|---|---|
| N | No. | % or Median (IQR) | N | No. | % or Median (IQR) | N | No. | % or Median (IQR) | |
| Maternal characteristics | |||||||||
| Race/ethnicity | |||||||||
| Black/Non-Hispanic | 117 346 | 36 873 | 31.4 | 10 379 | 3580 | 34.5 | 106 967 | 33 293 | 31.1 |
| Hispanic | 117 346 | 22 881 | 19.5 | 10 379 | 2141 | 20.6 | 106 967 | 20 740 | 19.4 |
| White/Non-Hispanic | 117 346 | 48 067 | 41.0 | 10 379 | 3885 | 37.4 | 106 967 | 44 182 | 41.3 |
| Asian/Pacific Islander | 117 346 | 5978 | 5.1 | 10 379 | 446 | 4.3 | 106 967 | 5532 | 5.2 |
| Other Non-Hispanic | 117 346 | 2611 | 2.2 | 10 379 | 235 | 2.3 | 106 967 | 2376 | 2.2 |
| Hypertension | 118 012 | 46 455 | 39.4 | 10 409 | 3142 | 30.2 | 107 603 | 43 313 | 40.3 |
| Diabetes | 117 620 | 13 495 | 11.5 | 10 364 | 941 | 9.1 | 107 256 | 12 554 | 11.7 |
| Antenatal steroids | 117 771 | 104 186 | 88.2 | 10 368 | 9125 | 87.4 | 107 403 | 95 061 | 88.2 |
| Chorioamnionitis | 118 175 | 14 903 | 12.7 | 10 438 | 1845 | 17.8 | 107 737 | 13 058 | 12.2 |
| Multiple gestation | 118 646 | 28 643 | 24.1 | 10 501 | 2225 | 21.2 | 108 145 | 26 418 | 24.4 |
| Vaginal delivery | 118 632 | 30 011 | 25.3 | 10 499 | 3466 | 33.0 | 108 133 | 26 545 | 24.5 |
| Infant characteristics | |||||||||
| BW, g | 118 644 | — | 1110 (834–1340) | 10 499 | — | 760 (612–985) | 108 145 | — | 1140 (875–1350) |
| GA, wk | 118 646 | — | 28 (26–30) | 10 501 | — | 25 (24–27) | 108 145 | — | 29 (27–30) |
| Small for GA | 118 323 | 22 662 | 19.2 | 10 406 | 1631 | 15.7 | 107 917 | 21 031 | 19.5 |
| Male sex | 118 626 | 59 415 | 50.1 | 10 498 | 5764 | 54.9 | 108 128 | 53 651 | 49.6 |
| Inborn | 118 650 | 102 492 | 86.4 | 10 501 | 8418 | 80.2 | 108 149 | 94 074 | 87.0 |
| Congenital anomaly | 118 639 | 6386 | 5.4 | 10 499 | 854 | 8.1 | 108 140 | 5532 | 5.1 |
| Early onset sepsis | 118 614 | 1353 | 1.1 | 10 491 | 217 | 2.1 | 108 123 | 1136 | 1.1 |
| NEC | 118 636 | 5799 | 4.9 | 10 498 | 1693 | 16.1 | 108 138 | 4106 | 3.8 |
| Pneumothorax | 118 615 | 4725 | 4.0 | 10 492 | 784 | 7.5 | 108 123 | 3.941 | 3.6 |
| Severe intraventricular hemorrhage | 109 722 | 8315 | 7.6 | 10 230 | 1802 | 17.6 | 108 123 | 6513 | 6.5 |
| Periventricular leukomalacia | 110 816 | 2919 | 2.6 | 10 251 | 653 | 6.4 | 99 492 | 2266 | 2.3 |
| Chronic lung disease | 101 125 | 30 034 | 29.7 | 8155 | 5059 | 62.0 | 92 970 | 24 975 | 26.9 |
| Retinopathy of prematurity | 95 179 | 30 313 | 31.8 | 8304 | 5121 | 61.7 | 86 875 | 25 192 | 29.0 |
| Length of stay, d | 118 650 | — | 64 (42–94) | 10 501 | — | 102 (63–141) | 108 149 | — | 62 (41–89) |
| Length of stay among survivors, d | 110 807 | — | 66 (45–96) | 8199 | — | 114 (86–150) | 102 608 | — | 64 (44–91) |
Infants with >1 pathogen identified were counted once. —, not applicable.