Table 2.

Mediation analysis of significant oxylipin variations through iron variations after meal challenge in HH

Oxylipin	Fasting values	Postprandial values	Size effect	Percentage of oxylipin variations mediated by iron variations
16-HDHA	0.93 [0.77–1.22]	0.76 [0.57–1.16]	−0.56	77
12(S)-HETrE	0.52 [0.44–0.79]	0.70 [0.57–0.96]	0.55	49
18-HETE	0.65 [0.55–0.81]	0.51 [0.45–0.62]	−0.54	49
16-HETE	0.37 [0.32–0.43]	0.31 [0.24–0.36]	−0.68	37
11-HEPE	0.22 [0.16–0.33]	0.15 [0.09–0.28]	−0.58	37
12-HETE	2.78 [2.53–3.48]	4.94 [2.65–10.27]	0.75	33
11-HDHA	1.33 [1.04–1.66]	0.93 [0.72–1.53]	−0.58	26
13-HODE	31.76 [27.78–39.51]	55.82 [44.44–65.82]	1.64	20
9,10,11-TriHOME	0.64 [0.53–1.05]	1.06 [0.84–1.38]	0.82	20
Tetranor-12(S)-HETE	0.10 [0.09–0.18]	0.18 [0.13–0.24]	0.75	20
9,10-DiHODE	0.24 [0.16–0.43]	0.55 [0.39–0.70]	0.98	16
12,13-DiHOME	3.95 [3.22–5.15]	6.58 [5.07–8.09]	0.97	16
PGF2a	4.27 [2.94–6.10]	3.88 [2.46–5.28]	−0.61	16
9-HOTrE	1.35 [0.84–1.62]	6.82 [3.93–9.12]	2.36	11
9-HODE	25.96 [19.46–35.50]	69.967 [47.08–103.69]	2.08	10
9,12,13-TriHOME	6.08 [4.21–11.76]	12.49 [9.77–17.06]	0.62	9
13-HOTrE	1.18 [1.00–1.71]	3.99 [3.11–4.84	2.08	8
15(16)-EpODE	17.61 [9.92–24.58]	55.45 [29.79–92.41]	1.38	8
19,20-DiHDPE	1.11 [0.91–1.31]	0.95 [0.83–1.06]	−0.54	7
15,16-DiHODE	6.18 [4.51–8.07]	23.68 [21.03–30.25]	2.59	4
9-Oxo-ODE	4.35 [0.84–1.62]	13.51 [8.17–15.88]	1.26	4
15-HODE	1.41 [1.18–2.02]	9.19 [6.20–11.18]	2.50	0

Data are presented as median [quartile 1 – quartile 3].