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. 2024 Mar 21;42(3):211–220. doi: 10.1159/000538399

Table 2.

Major factors driving PPI overuse

Healthcare professionals Patients
Timesaving (vs. lifestyle counselling) Desire for simple, easy solution; minimal effort
Over-diagnosis of “GORD” on a clinical basis Lack of proper and timely review of prescription
Misconceptions regarding “refractory GORD” Misconception that PPIs are curative
Unnecessary continuation of hospital-initiated prescriptions Belief that reflux-like symptoms are caused by excessive acid
Limited access to investigations and/or secondary care Reluctance or failure to modify behaviour
Limited alternative therapies Ease of access to PPIs in the pharmacy
Belief that all reflux-like symptoms are caused by acid reflux Poor understanding of alternative therapeutic options
ENT-initiated for suspected reflux syndrome without a long-term plan
Missing information in electronic patient records regarding indication

ENT, ear, nose, and throat department; GORD, gastro-oesophageal reflux disease; PPI, proton pump inhibitor.