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Summary of 3 types of 5-ASA sustained-release oral formulations in Japan
| Type of formulation | |||
|---|---|---|---|
| time-dependent | pH-dependent | MMX | |
| Indication approved in Japan | UC (except severe), CD | UC (except severe) | UC (except severe) |
| Regimen | TID, BID, OD | TID, OD | OD |
| Maximum dose, mg/day | 4,000 | 3,600 | 4,800 |
| Tablets | 250 mg, 500 mg | 400 mg | 1,200 mg |
| Granules | 94% | None | None |
