Table 3.

ANCOVA results for FD symptoms with regard to improvements with STW 5-II versus placebo after 28 days

GIS item	MD (95% CI)	p value
Epigastric pain	0.39 (0.32–0.55)	<0.0001*
Fullness	0.38 (0.20–0.56)	<0.0001*
Early satiety	0.36 (0.17–0.55)	0.0002*
Nausea	0.28 (0.08–0.47)	0.0071*
Vomiting	0.06 (−0.25 to 0.37)	0.6950
Abdominal cramps	0.32 (0.14–0.50)	0.0005*
Acid eructation/heartburn	0.45 (0.25–0.65)	<0.0001*
Sickness	0.27 (0.08–0.46)	0.0052*
Loss of appetite	0.33 (0.13–0.54)	0.0018*
Retrosternal discomfort	0.52 (0.32–0.71)	<0.0001*
Sum score	2.44 (1.57–3.3)	<0.0001*

CI, confidence interval; GIS, gastrointestinal symptom.