Table 5.
RAR/RXR target genes involved in liver Inflammation.
Target gene | Regulation | Function | Species | Cell type | References |
---|---|---|---|---|---|
IFN-γ (RAR/RXR) | Repression | The cytokine of the immune system related to the T helper type 1 (Th1) response to infection | Human | T lymphoblastoid cell | [106] |
NF-κB (RAR/RXR) | Repression | The transcription factor for regulating expression of proinflammatory genes, including cytokines, chemokines, and adhesion molecules | Human | THP-1 cells | [108] |
AP-1 (RAR/RXR) | Repression | The transcription factor for regulating expression of proinflammatory genes, | Human | THP-1 cells | [108] |