Table 3:
Multivariable analysis for progression-free survival 2 and overall survival among patients with resectable disease
| PFS2 | OS | |||||
|---|---|---|---|---|---|---|
| Characteristic | n | HR (95% CI) | p | HR (95% CI) | p | |
| Age | ||||||
| <60 years | 97 | Ref | Ref | |||
| ≥60 years | 37 | 1.35 (0.89 – 2.03) | 0.16 | 2.25 (1.26 – 4.04) | 0.006 | |
| CRS | ||||||
| No | 7 | Ref | Ref | |||
| Yes | 127 | 0.42 (0.19 – 0.92) | 0.03 | 0.28 (0.11 – 0.67) | 0.004 | |
| Chemotherapy | ||||||
| No | 53 | Ref | Ref | |||
| Yes | 81 | 1.21 (0.81 – 1.82) | 0.35 | 1.49 (0.84 – 2.62) | 0.17 | |
| History of adjuvant therapy | ||||||
| No | 94 | Ref | Ref | |||
| Yes | 40 | 1.17 (0.78 – 1.76) | 0.45 | 1.08 (0.60 – 1.94) | 0.81 | |
CRS = cytoreductive surgery. HR = hazard ratio. OS = overall survival. PFS2 = progression-free survival following 1st recurrence. Ref = reference. 95% CI = 95% confidence interval. p = p-value