Table 2.

Meta-Analysis of the Association of CXCL12 rs1801157 Polymorphism and Breast Cancer

	Genetic Model	Type of Model	Heterogeneity		Odds ratio			Publication Bias
			I2(%)	PH	OR	95% CI	POR	PBeggs	PEggers
Overall	A vs. G	Random	77.34	≤0.001	1.18	0.951-1.464	0.134	0.858	0.961
	AG vs. GG	Random	84.21	≤0.001	1.183	0.843-1.655	0.331	0.858	0.709
	AA vs. GG	Fixed	38.6	0.101	1.35	1.050-1.734	0.019	0.858	0.909
	AA+AG vs. GG	Random	83.66	≤0.001	1.212	0.881-1.668	0.237	0.72	0.941
	AA vs. AG+GG	Fixed	0	0.676	1.266	0.994-1.613	0.056	0.72	0.941
Caucasians	A vs. G	Fixed	0	0.957	1.308	1.117-1.531	0.001	1	0.45
	AG vs. GG	Fixed	0	0.644	1.325	1.071-1.640	0.01	1	0.89
	AA vs. GG	Fixed	0	0.947	1.753	1.191-2.581	0.004	1	0.653
	AA+AG vs. GG	Fixed	0	0.724	1.383	1.128-1.696	0.002	1	0.819
	AA vs. AG+GG	Fixed	0	0.807	1.504	1.038-2.179	0.031	1	0.685
Asians	A vs. G	Random	91.44	≤0.001	1.027	0.643-1.641	0.911	0.734	0.514
	AG vs. GG	Random	94.41	≤0.001	0.952	0.438-2.070	0.902	0.734	0.378
	AA vs. GG	Random	69.83	0.019	1.071	0.566-2.024	0.833	1	0.52
	AA+AG vs. GG	Random	94.12	≤0.001	0.984	0.477-2.028	0.964	0.734	0.44
	AA vs. AG+GG	Fixed	9.38	0.346	1.104	0.787-1.547	0.568	1	0.947
Mixed	A vs. G	Fixed	0	0.684	1.322	0.964-1.813	0.083	1	0.629
	AG vs. GG	Fixed	0	0.922	1.436	0.976-2.114	0.066	0.296	0.137
	AA vs. GG	Fixed	0	0.5	1.372	0.514-3.661	0.528	1	0.948
	AA+AG vs. GG	Fixed	0	0.849	1.432	0.986-2.079	0.06	1	0.47
	AA vs. AG+GG	Fixed	0	0.494	1.212	0.458-3.204	0.698	1	0.967