Table 7.

Protox-II Toxicity Estimations on Cannabinoids: THC, CBD, and THCV

		THC		CBD		THCV
Predicted LD50		482 mg/kg		500 mg/kg		482 mg/kg
Predicted Toxicity Class		4		4		4
Toxicity Model Report
Classification	Target	Prediction	Prob.	Prediction	Prob.	Prediction	Prob.
Toxicity end points	Hepatotoxicity	Inactive	0.93	Inactive	0.79	Active	0.85
Toxicity end points	Carcinogenicity	Inactive	0.86	Inactive	0.66	Active	0.84
Toxicity end points	Immunotoxicity	Active	0.99	Active	0.93	Active	0.95
Toxicity end points	Mutagenicity	Inactive	0.77	Inactive	0.85	Inactive	0.74
Toxicity end points	Cytotoxicity	Inactive	0.84	Inactive	0.87	Inactive	0.83