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. 2024 Jun 11;42(16):3547–3554. doi: 10.1016/j.vaccine.2024.04.060

Table 2.

Table of patients meeting the EU ARI and the EU ILI case definitions among study sites using the EU ARI case definition to recruit patients (n = 31 645), study on effect of case definition on influenza vaccine effectiveness, VEBIS primary care multicentre case-control study, EU/EEA, 2022–23.

Meets ILI case definition
Meets ARI case definition No Yes Missingb Total
All No 2 031 0 0 2031
Yes 2 564 24 243 470 27 277
Missinga 23 0 2 314 2337
Total 4 618 24 243 2 784 31 645



Influenza cases No 439 0 0 439
Yes 160 6 524 31 6715
Missinga 0 0 479 479
Total 599 6 524 510 7633



Controls No 1 592 0 0 1592
Yes 2 404 17 719 439 20 562
Missinga 23 0 1 835 1858
Total 4 019 17 719 2 274 24 012
a

The ARI case definition was coded as “missing” among patients with missing information for “sudden onset” or where at least one of the four respiratory symptoms was coded as missing and none was coded as “yes”.

b

The ILI case definition was coded as “missing” among patients with missing information for “sudden onset” or where at least one of the four systemic symptoms was coded as missing and none was coded as “yes” or where at least one of the three respiratory symptoms (cough, sore throat, shortness of breath) was coded as missing and none was coded “yes”.