Table 1.
Characteristics of the patients, n = 84.
| Median age (range), years | 69 (38–84) |
|---|---|
| Gender, male, | 60/84 (71%) |
| ECOG, n (%) | |
| 0 | 54 (64.3)28 (33.3) |
| 1 | 2 (2.4) |
| 2 | |
| Binet stage, n (%) | |
| A | 15 (18.3) |
| B | 40 (48.8) |
| C | 27 (32.9) |
| Rai stage, n (%) | |
| 0 | 3 (3.7) |
| I | 14 (17.1) |
| II | 29 (35.4) |
| III | 14 (17.1) |
| IV | 22 (26.8) |
| CIRS score, median, range | 2 (0–5) |
| IGHV mutational status, n (%) | |
| Mutated | 28/72 (39) |
| Unmutated | 44/72 (61) |
| Genetic features of CLL,a n (%) | |
| 17 deletion | 5/84 (6) |
| 11q deletion | 9/84 (10.7) |
| 13q deletion | 37/84 (44.1) |
| Trisomy 12 | 20/84 (23.8) |
| Complex karyotype,b n (%) | 7/84 (8.3) |
| TP53 mut, n (%) | 6/84 (7.1) |
CIRS, Cumulative illness rating scale; ECOG, Eastern Cooperative Oncology Group performance status.
a
Data available in 78 cases.
b
Data available in 60 cases.