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. 2024 Mar 28;9(6):1499–1512. doi: 10.1038/s41564-024-01672-3

Extended Data Table 2.

Affinity data

Averaged Kinetic Parameters
ka1 (104M−1s−1) kd1 (10−3s−1) kD1 (e-9) Bmax1 (Hz)
LDL 25.5 1.12 3 70
CCHFV Gc 1.3 0.059 3.3 64
Gc + Gn 2.1 0.00867 0.272 (272pM) 7

The QCM data were assessed and analysed using the Evaluation (Attana AB) and TraceDrawer software (Ridgeview Instruments), employing 1:1 or 1:2 binding models to calculate kinetic parameters, including rate constants (ka, kd), dissociation equilibrium constant (KD), and maximum binding capacity (Bmax).