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SH-NPs fitting release model and coefficient.
| Model | Fitting equation | R2 |
|---|---|---|
| Zero-order equation | Mt/M∞＝1.15422t＋12.941 | 0.86368 |
| First-order equation | Mt/M∞＝56.27374（1-e−0.10463t） | 0.93837 |
| Higuchi equation | Mt/M∞＝8.74945t1/2＋3.09324 | 0.9855 |
| Ritger-Peppas equation | Mt/M∞ = 12.66609（t0.41,006） | 0.99393 |
M∞ is accumulative drug-release at time, Mt is accumulative drug-release at time t, Mt/M∞ is accumulative release rate at time t, t is time.
