Figure 2.

Population structure and genetic affinities of the newly sequenced individuals

(A) Principal-component analysis (PCA) of merged dataset with Human Origins samples (see Figure S4 for replication with pseudo-haploid calls), with (B) representing a zoomed inset focusing on the study populations and their position on the ANI-ASI genetic ancestry cline. Population labels in gray represent the mean location of all samples in PCA. For populations sampled specifically in this study, mean locations are represented as larger circles of the same color. (C) ADMIXTURE results (K = 7) showcasing genetic similarity across Southwest Indian populations in relation to African, East Asian, Central Asian, Middle Eastern, and other South Asian populations. We removed some population labels for visual clarity (see Figure S5 for a full set of labels; Figure S6 for replication with pseudo-haploid calls). Populations sampled specifically in this study are represented using bolded population labels. (D) Outgroup-f₃ statistics results for the study populations relative to other South Indian populations. See Figure S8 for an extended panel consisting of worldwide populations and Figure S9 for replication with pseudo-haploid calls.