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. 2024 Apr 25;67(7):1413–1428. doi: 10.1007/s00125-024-06153-0

Table 3.

Serum metabolites significantly differing between non-diabetes control participants and participants with type 1 diabetes at rest (baseline)

Metabolite Fold change Log2(fold change) p value
NEFA C22:0 1.6834 0.75142 3.63×10−8
Lactic acid 1.2215 0.28862 1.23×10−5
NEFA C20:0 1.6568 0.72838 4.45×10−5
Succinate 1.3117 0.39145 0.00011
Malic acid 1.3939 0.47913 0.00116
BAIBA 0.65902 −0.60161 0.001335
AC C18:1 1.5043 0.58909 0.001857
AC C16:1 1.724 0.78579 0.003675
Taurohyodeoxycholic acid 0.2695 −1.8917 0.020038
cis-Aconitate 1.5488 0.63113 0.025681
cAMP 1.4947 0.57985 0.044342

The table shows the fold change and log2(fold change) of metabolites in the serum of participants with type 1 diabetes compared with control participants at the baseline time point of the aerobic exercise study (n=30 for both groups)

p value was generated by two-tailed Student’s t test