Table 4.
ANOVA showing serum metabolites altered following aerobic exercise in participants with type 1 diabetes
| Metabolite | F value | p value | FDR | Significant group differences (Tukey’s post hoc test) |
|---|---|---|---|---|
| AC C10:1 | 16.219 | 1.19×10−6 | 6.61×10−5 | E-B; E-R |
| Lactic acid | 15.83 | 1.57×10−6 | 6.61×10−5 | E-B; E-R |
| AC C6 | 14.51 | 4.11×10−6 | 0.000115 | E-B; E-R |
| NEFA C18:3 | 13.475 | 8.87×10−6 | 0.000161 | E-B; E-R |
| NEFA C14:0 | 13.372 | 9.59×10−6 | 0.000161 | E-B; E-R |
| AC C12 | 12.34 | 2.10×10−5 | 0.000294 | E-B; E-R |
| AC C12:1 | 12.045 | 2.63×10−5 | 0.000316 | E-B; E-R |
| Succinate | 11.746 | 3.32×10−5 | 0.000348 | E-B; E-R |
| NEFA C18:1 | 11.365 | 4.46×10−5 | 0.000384 | E-B; E-R |
| NEFA C17:1 | 11.335 | 4.57×10−5 | 0.000384 | E-B; E-R |
| NEFA C20:4 | 10.868 | 6.59×10−5 | 0.000503 | E-B; E-R |
| AC C14:1 | 9.5497 | 0.000189 | 0.001264 | E-B; E-R |
| AC C10 | 9.5065 | 0.000196 | 0.001264 | E-B; E-R |
| NEFA C16:1 | 9.3802 | 0.000217 | 0.0013 | E-B; E-R |
| NEFA C16:0 | 8.9702 | 0.000303 | 0.001695 | E-B; E-R |
| NEFA C15:0 | 8.3633 | 0.000499 | 0.00262 | E-B; E-R |
| NEFA C16:2 | 8.1612 | 0.00059 | 0.002917 | E-B; E-R |
| AC C14:2 | 7.8697 | 0.000753 | 0.003513 | E-B; E-R |
| NEFA C20:3 | 7.6202 | 0.000928 | 0.004104 | E-B; E-R |
| NEFA C20:5 | 6.578 | 0.002253 | 0.009463 | E-B; E-R |
| AC C8 | 6.4956 | 0.002419 | 0.009676 | E-B; E-R |
| NEFA C22:4 | 5.6039 | 0.005255 | 0.020064 | E-B; E-R |
| Glycolithocholic acid | 5.0903 | 0.008272 | 0.030209 | E-B |
| NEFA C12:0 | 4.8637 | 0.010121 | 0.035424 | E-B; E-R |
| Malic acid | 4.8019 | 0.010696 | 0.035939 | E-B; E-R |
N=30
p value generated by one-way ANOVA
B, baseline; E, aerobic exercise; FDR, false discovery rate; R, post-exercise 1 h recovery