Table 1.
Patient characteristics at ICU admission
| Characteristics | Overall cohort (n = 1313) | Immuno-compromised patients (n = 271) | Non-immuno-compromised patients (n = 1042) |
|---|---|---|---|
| Age (years) | 62 (50–70) | 65 (54–72) | 61 (50–70) |
| Male gender | 8793 (66.9) | 165 (60.9) | 714 (68.5) |
| Body mass index (kg/m2) | 27.4 (23.7–32.7)1 | 25.6 (22.5–30.1)2 | 27.9 (24.0–33.7)3 |
| Smoking | 366 (27.9) | 72 (26.6) | 294 (28.2) |
| Chronic alcohol use | 216 (16.5) | 25 (9.2) | 191 (18.3) |
| Diabetes mellitus | 390 (29.7) | 71 (26.2) | 319 (30.6) |
| Cardiovascular disease | 719 (54.8) | 164 (60.5) | 555 (53.3) |
| Hypertension | 642 (48.9) | 143 (52.8) | 499 (47.9) |
| Coronary-artery disease | 188 (14.3) | 39 (14.4) | 149 (14.3) |
| Heart failure | 154 (11.7) | 42 (15.5) | 112 (10.7) |
| Venous thromboembolic disease | 86 (6.5) | 28 (10.3) | 58 (5.6) |
| Lung disease | 284 (21.6) | 76 (28.0) | 208 (20.0) |
| Chronic respiratory disease | 250 (19.0) | 70 (25.8) | 180 (17.3) |
| COPD | 177 (13.5) | 37 (13.7) | 140 (13.4) |
| Chronic kidney disease | 128 (9.7) | 40 (14.8) | 88 (8.4) |
| Liver cirrhosis | 56 (4.3) | 16 (5.9) | 40 (3.8) |
| Recent surgery | 111 (8.5) | 39 (14.4) | 72 (6.9) |
| Recent antibiotic treatment for > 48 h | 327 (24.9) | 107 (39.5) | 220 (21.1) |
| Recent hospitalization for > 48 h | 351 (26.7) | 132 (48.7) | 219 (21.0) |
| Known colonization with MDR bacteria | 149 (11.3) | 48 (17.7) | 101 (9.7) |
| COVID-19 | 488 (37.2) | 64 (23.6) | 424 (40.7) |
| SAPS-II | 39 (29–55)4 | 44 (34–57) | 38 (28–54)5 |
| SOFA score | 4 (2–8)6 | 4 (2–7)7 | 4 (2–8)8 |
| Type of ICU admission | |||
| Medical | 1228 (93.5) | 256 (94.5) | 972 (93.5) |
| Surgical | 853 (6.5) | 15 (5.5) | 70 (6.7) |
Values are as number (%), or median (25th to 75th percentiles)
COPD chronic obstructive pulmonary disease, ICU intensive care unit, MDR multidrug-resistant, SAPS-II simplified acute physiology score II, SOFA sequential organ failure assessment
Missing values: 1111, 215, 396, 42, 52, 680, 719, 861