Table 1.
Cross table for burden of enlarged perivascular spaces in 147 patients with chronic adult hydrocephalus.
| Characteristic | N | Low ePVS burden, 34 (23%) | High ePVS burden, 113 (77%) | p value | q valued |
|---|---|---|---|---|---|
| Sex | 147 | 0.034b | 0.086 | ||
| Females | 9 (26%) | 53 (47%) | |||
| Males | 25 (74%) | 60 (53%) | |||
| Hydrocephalus morphology | 147 | 0.16b | 0.26 | ||
| Tetra-ventricular | 15 (44%) | 35 (31%) | |||
| Tri-ventricular | 19 (56%) | 78 (69%) | |||
| Aqueductal CSF stroke volume (μL) | 147 | 158 (191)a | 80 (93) | 0.005c | 0.024 |
| Age at diagnosis (years) | 147 | 72 (13)a | 74 (12) | 0.20c | 0.26 |
| Hydrocephalus etiology | 147 | 0.31b | 0.314 | ||
| Secondary | 8 (24%) | 18 (16%) | |||
| Unknown | 26 (76%) | 95 (84%) |
N: number. The patients were considered with a high enlarged perivascular spaces (ePVS) burden when at least 11 ePVS were found at both the levels of basal ganglia and of periventricular parenchyma or with low ePVS burden in the case of fewer ePVS at the same anatomic levels.
aMedian (interquartile range).
bPearson's Chi-squared test.
cWilcoxon rank sum test.
dFalse discovery rate correction for multiple testing.