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. 2024 Jun 5;14:12966. doi: 10.1038/s41598-024-63926-8

Table 2.

Cross table for secondary versus. unknown etiology of ventriculomegaly in 147 patients with chronic adult hydrocephalus.

Characteristic N Secondary, 26 (18%) Unknown, 121 (82%) p value q-value
Sex 147 0.99b 0.994d
 Females 11 (42%) 51 (42%)
 Males 15 (58%) 70 (58%)
Hydrocephalus morphology 147 0.19b 0.494d
 Tetra-ventricular 6 (23%) 44 (36%)
 Tri-ventricular 20 (77%) 77 (64%)
Aqueductal CSF stroke volume (μL) 147 78 (158)a 89 (127) 0.53c 0.66d
Age at diagnosis (years) 147 70 (16)a 74 (12) 0.20c 0.49d
Low burden of ePVS 147 8 (31%) 26 (21%) 0.31b 0.51d

N: number. The patients were considered with a low enlarged perivascular spaces (ePVS) burden when less than 11 ePVS were found at both the levels of basal ganglia and of periventricular parenchyma.

aMedian (interquartile range).

bPearson's Chi-squared test.

cWilcoxon rank sum test.

dFalse discovery rate correction for multiple testing.