Table 3.

The predictive performance comparison between multi-omics signatures, clinical TNM staging and RADL signature for pCR.

Parameters	Difference of AUC	95 % CI	Z statistic	P value
Multi-omics vs. clinical TNM staging system
Train	0.361	0.215 - 0.508	4.834	< 0.0001
Test	0.309	0.0909 - 0.528	2.776	0.0055
External validation	0.360	0.0514 - 0.396	2.544	0.0110
Multi-omics vs. RADL signature
Train	0.0843	0.0312 - 0.138	3.109	0.0019
Test	0.0238	−0.0591 - 0.107	0.563	0.5735
External validation	0.132	0.0590 - 0.205	3.547	0.0004