Table 1.
Patient and Tumor Characteristics
| Age at initial diagnosis (y) | ||
|---|---|---|
| Median | 43 | |
| Range | 25–75 | |
| KPS prior to PRDR (n) | ||
| 100 | 16 (28%) | |
| 90 | 22 (38%) | |
| 80 | 12 (21%) | |
| 70 | 2 (3%) | |
| 60 | 2 (3%) | |
| 50 | 4 (7%) | |
| Bilateral hemisphere or corpus callosum involvement (n) | 29 (50%) | |
| Brainstem or thalamus involvement (n) | 10 (17%) | |
| Herniation or midline shift (n) | 5 (9%) | |
| Histology (n) | Astrocytoma | 29 (50%) |
| Oligodendroglioma | 23 (40%) | |
| Oligoastrocytoma | 6 (10%) | |
| Tumor markers at the time of diagnosis (n) | ||
| MGMT methylation | Yes | 13 (22%) |
| No | 22 (38%) | |
| Unknown | 23 (40%) | |
| IDH mutated | Yes | 15 (26%) |
| No | 12 (21%) | |
| Unknown | 31 (53%) | |
| 1p/19q co-deleted | Yes | 16 (28%) |
| No | 21 (36%) | |
| Unknown | 21 (36%) | |
| Grade at time of recurrence (n) | ||
| No change (grade 2) | 18 (31%) | |
| Grade 3 | 22 (38%) | |
| Grade 4 | 18 (31%) | |