Table 1.

Probability of success ( ${\mathrm{P}}_{\mathrm{s}}$ ) for GDC-0810 nanosuspension formulations, predicted by ${\mathrm{FASA}}_{\mathrm{p}}$ through the logistic regression in Equation (3). ${\mathrm{FASA}}_{\mathrm{p}}$ is extracted as an average from MD simulations for each excipient and directly from a single crystal structure in the case of no excipient (Figure 6).

Excipient	Neutral ${\mathbf{P}}_{\mathbf{s}}$	Ionic ${\mathbf{P}}_{\mathbf{s}}$
SDS	0.447	0.997
SOS	0.510	0.998
SDC	0.303	0.997
PEG	0.271	0.996
PPG	0.153	0.992
Poloxamer	0.221	0.994
Tween 80	0.271	0.995
no excipient	0.161	0.871