Table 1.
Significantly changed latent variables in each condition
| LV_ID | Genotype | Region | Adjusted p value |
|---|---|---|---|
| LV3 | WT | Microglia | 0.0385 |
| LV40 | AD | Astrocyte | 0.0408 |
| LV40 | AD | Microglia | 0.0159 |
| LV41 | WT | Microglia | 0.0493 |
| LV46 | WT | Astrocyte | 0.0416 |
| LV46 | WT | Microglia | 0.0159 |
| LV47 | WT | Astrocyte | 0.0165 |
| LV48 | WT | Microglia | 0.0385 |
| LV50 | AD | Astrocyte | 0.0385 |
| LV51 | WT | Microglia | 0.0377 |
| LV56 | AD | Microglia | 0.0165 |
| LV62 | AD | Microglia | 0.0398 |
| LV74 | AD | Microglia | 0.0422 |
| LV82 | AD | Microglia | 0.0061 |
| LV86 | WT | Microglia | 0.0398 |
| LV99 | AD | Astrocyte | 0.0385 |
| LV99 | AD | Microglia | 0.0159 |
| LV99 | WT | Microglia | 0.0086 |
| LV103 | AD | Microglia | 0.0385 |
| LV105 | AD | Microglia | 0.0398 |
| LV115 | WT | Microglia | 0.0007 |
| LV121 | AD | Microglia | 0.0398 |
| LV128 | AD | Microglia | 0.0086 |
| LV140 | AD | Microglia | 0.0385 |
| LV141 | AD | Microglia | 0.0214 |
| LV142 | WT | Astrocyte | 0.0057 |
| LV155 | AD | Astrocyte | 0.0477 |
| LV155 | WT | Astrocyte | 0.0165 |
| LV156 | WT | Astrocyte | 0.0497 |
| LV159 | WT | Microglia | 0.0165 |
| LV196 | AD | Microglia | 0.0165 |
Gene expression data were converted into latent space and tested for differential expression during aging. WT, wild type; AD, Alzheimer disease; LV, latent variable.