FIGURE 5.

DCTN2 is highly expressed in HCC and correlates with poor prognosis. (A) Boxplot showing the expression of DCTN2 in tumour and normal tissues in various GEO HCC datasets. (B) Higher DCTN2 expression was observed in patients with late TNM stage, higher AFP levels, poor differentiation grade and vascular invasion. (C, D) Kaplan–Meier and univariate analysis showing high DCTN2 associated with poor prognosis. (E) DCTN2 protein was higher in HCC tissues than normal tissues from HPA database.*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, NS: not significant.